Issue

Vol 132 No 1491: 8 March 2019

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Issue Summary

SUMMARY

Relationship between estimated glomerular filtration rate and incident cardiovascular disease in an ethnically diverse primary care cohort

This is a large study examining whether there is a relationship between kidney function (eGFR) and the risk of having a cardiovascular event such as a heart attack or stroke in New Zealanders. The esti-mated Glomerular Filtration Rate (eGFR) result indicates how well the kidneys filter waste from the blood and it can identify the presence of kidney damage. The study found that participants with worse kidney function were more likely to go on to have a cardiovascular event. Patients included in the study attended their family doctor for their heart and diabetes check. At this check, a doctor or nurse collects information on any risk factors and calculates a patient s risk of having a heart attack or stroke over the next five years. The CVD risk is used to guide treatment decisions. After taking into account other CVD risk factors such as smoking, blood pressure and cholesterol levels, Mori and Pa-cific patients without diabetes or CVD were at higher risk of developing heart disease with worsen-ing eGFR compared to Europeans. Indian people had similar risk and Other Asians had lower risk compared to Europeans. Further studies are needed to understand whether including kidney func-tion as part of the heart and diabetes check could improve the accuracy of risk prediction and lead to more tailored care of patients seeing their doctor.

SUMMARY

Relationship between estimated glomerular filtration rate and incident cardiovascular disease in an ethnically diverse primary care cohort

This is a large study examining whether there is a relationship between kidney function (eGFR) and the risk of having a cardiovascular event such as a heart attack or stroke in New Zealanders. The esti-mated Glomerular Filtration Rate (eGFR) result indicates how well the kidneys filter waste from the blood and it can identify the presence of kidney damage. The study found that participants with worse kidney function were more likely to go on to have a cardiovascular event. Patients included in the study attended their family doctor for their heart and diabetes check. At this check, a doctor or nurse collects information on any risk factors and calculates a patient s risk of having a heart attack or stroke over the next five years. The CVD risk is used to guide treatment decisions. After taking into account other CVD risk factors such as smoking, blood pressure and cholesterol levels, Mori and Pa-cific patients without diabetes or CVD were at higher risk of developing heart disease with worsen-ing eGFR compared to Europeans. Indian people had similar risk and Other Asians had lower risk compared to Europeans. Further studies are needed to understand whether including kidney func-tion as part of the heart and diabetes check could improve the accuracy of risk prediction and lead to more tailored care of patients seeing their doctor.