26th July 2019, Volume 132 Number 1499

Yu-Jen Chen, Christopher Lim, Jacob McCormick

Iron-deficiency anaemia is the most common form of anaemia worldwide. The incidence is particularly high in patients with colorectal cancer, as unexplained iron deficiency anaemia often prompts further investigation for…

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Abstract

Iron-induced hypophosphatemia represents an increasingly recognised complication of iron infusion. A 34-year-old woman presented for surgical management of her colorectal cancer. Post-operative blood tests revealed severe hypophosphatemia, resistant to oral phosphate supplementation and large volumes of intravenous phosphate replacement. Further questioning and biochemical investigation led to the recognition of iron-induced hypophosphatemia as a contributory cause, secondary to iron infusion administered as part of pre-operative optimisation. Early consideration, diagnosis and management of this complication has the potential to reduce fluid burden associated with intravenous phosphate supplementation and optimise post-operative care.

Author Information

Yu-Jen Chen, Department of General Surgery, Royal Melbourne Hospital, Vic, Australia;
Christopher Lim, Department of General Medicine, Royal Melbourne Hospital, Vic, Australia;
Jacob McCormick, Department of General Surgery, Royal Melbourne Hospital, Vic, Australia. 

Correspondence

Yu-Jen Chen, Department of General Surgery, Royal Melbourne Hospital, 300 Grattan Street, Parkville, Victoria, 3052, Australia.

Correspondence Email

yujen.chen@mh.org.au

Competing Interests

Nil.

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