The New Zealand Ministry of Health has reported colorectal cancer (CRC) as the third most common cancer after prostate and breast, comprising almost 14% of all those registered in 2012,…
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In this article, the authors describe the patterns of disease recurrence in patients having curative surgery for colorectal cancer at a hospital in New Zealand over a three-year period. With five years of follow-up data, one in four patients experienced the cancer returning and this is in keeping with data reported in the worldwide literature. Recurrence most commonly occurred within the first two years, and the liver and lungs were the most common sites of recurrence.
To describe the patterns of recurrence in a contemporaneous cohort of patients undergoing surgery with curative intent for colorectal adenocarcinoma at a New Zealand hospital with five-year follow-up.
Patients with colorectal cancer undergoing potentially curative surgery between January 2010 and December 2012 were followed up for a median of 61 months with three-monthly CEA (carcinoembryonic antigen), a colonoscopy after one year and yearly computed tomography scans of the chest, abdomen and pelvis for the first three years.
Overall, 59/237 (24.9%) of patients experienced disease recurrence, the most common sites being the liver, followed by the lung and local recurrence. Recurrence rates did not differ significantly between colon and rectal cancer and ranged from 5.1% in stage I to 60% in stage IV. Seventy-three percent of all recurrences were observed within the first 24 months post-operatively.
While New Zealand outcomes in colorectal cancer have historically compared unfavourably against international standards, the outcomes observed in this cohort are encouraging and may reflect advances in care, including multidisciplinary team discussion, increased use of adjuvant therapy, surgical subspecialisation and protocolled surveillance and follow-up.