10th November 2017, Volume 130 Number 1465

Helen Lunt, Ben Hudson

Metformin has been used in the treatment of type 2 diabetes for 60 years.1 Past fashions in prescribing have seen metformin come in to and go out of favour. Metformin…

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Author Information

Helen Lunt, Clinical Associate Professor, Department of Medicine, University of Otago, Christchurch, Physician, Diabetes Centre, Canterbury District Health Board, Christchurch;
Ben Hudson, Senior Lecturer, Department of General Practice, University of Otago, Christchurch, General Practitioner, Lyttelton Health Centre, Lyttelton. 

Correspondence

Helen Lunt, Diabetes Physician, Diabetes Centre, 550 Hagely Ave, Christchurch 8011.

Correspondence Email

helen.lunt@cdhb.health.nz

Competing Interests

Nil.

References

  1. Bailey CJ. Metformin: historical overview. Diabetologia. 2017; 60:1566–76.
  2. Murray P, Norris H, Metcalfe S, et al. Dispensing patterns for antidiabetic agents in New Zealand; are the guidelines being followed? N Z Med J 2017; 130(1465):12–18.
  3. Bpac. Managing patients with type 2 diabetes: from lifestyle to insulin. BPJ. 2015; 72:33–42. http://www.bpac.org.nz/BPJ/2015/December/diabetes.aspx Accessed 2 October 2017. 
  4. Sharma M, Nazareth I, Petersen I. Trends in incidence, prevalence and prescribing in type 2 diabetes mellitus between 2000 and 2013 in primary care: a retrospective cohort study BMJ Open 2016;6:e010210. doi: 10.1136/bmjopen-2015-010210
  5. www.medsafe.govt.nz/medicines (Accessed 11 October 2017).
  6. Jayathissa S, Dixon P, Bruce R, Reith D. Refining metformin prescribing in New Zealand. N Z Med J. 2017; 130:49–53.
  7. Crowley MJ, Diamantidis CJ, McDuffie JR, et al. Clinical Outcomes of Metformin Use in Populations with Chronic Kidney Disease, Congestive Heart Failure, or Chronic Liver Disease: A Systematic Review. Ann Intern Med. 2017; 166:191–200. 
  8. Purnell TS, Joy S, Little E, et al. Patient Preferences for Noninsulin Diabetes Medications: A Systematic Review. Diabetes Care. 2014; 37:2055–2062. 
  9. Chapman LE, Darling AL, Brown JE. Association between metformin and vitamin B12 deficiency in patients with type 2 diabetes: A systematic review and meta-analysis. Diabetes Metab. 2016; 42:316–27. 
  10. Vijan S, Sussman JB, Yudkin JS, Hayward RA. Effect of patients’ risks and preferences on health gains with plasma glucose level lowering in type 2 diabetes mellitus. JAMA Intern Med. 2014; 174:1227–34. 

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