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The New Zealand Medical Journal

 Journal of the New Zealand Medical Association, 27-October-2006, Vol 119 No 1244

Recent population trends in amphetamine use in New Zealand: comparisons of findings from national household drug surveying in 1998, 2001, and 2003
Chris Wilkins, Paul Sweetsur, Sally Casswell
Abstract
Aim To track recent trends in the population prevalence, availability, price, and harm of amphetamine in New Zealand.
Design National household drug surveys were conducted in 1998, 2001, and 2003 using the same Computer Assisted Telephone Interview (CATI) methodology. General population random digit dial samples of 15–45 year olds were compared between the three survey waves (n=5475 in 1998; n=5504 in 2001; n=3042 in 2003).
Findings The proportion of the sample who had ever used amphetamine increased in 2001 compared to 1998 (11.0% versus 7.6%, p<0.0001) and then decreased in 2003 compared to 2001 (9.0% versus 11.0%, p=0.0066). The last year use of amphetamine increased in 2001 compared to 1998 (5.0% versus 2.9%, p<0.0001) and then did not significantly change in 2003 compared to 2001 (4.0% versus 5.0%, p=0.0466). The proportion of last year amphetamine users who said that the availability of amphetamine had become ‘harder’ compared to 12 months ago was higher in 2003 compared to 2001 (24.5% versus 12.4%, p=0.0284). Approximately 3 out of 10 amphetamine users reported harm to at least one area of their life from amphetamine use in 2001 and 2003. Harm to ‘energy and vitality’, ‘financial position’, and ‘health’ were the areas of life most commonly reported harmed from amphetamine use in both 2001 and 2003.
Conclusions Amphetamine remains a drug of serious concern in New Zealand. There is evidence of a levelling out in the prevalence of use and some evidence of a relative decline in availability. After 2001, wider public awareness of the health risks associated with methamphetamine use, and increasing law enforcement and legislative focus on methamphetamine, may have contributed to the stabilisation of the situation by 2003.

Since the late 1990s, New Zealand has experienced dramatic increases in detections of potent amphetamines, such as methamphetamine.1 The number of clandestine amphetamine laboratories detected each year by the New Zealand Police increased from just 2 in 1998, to 41 in 2001, and to 202 in 2003.2,3 Related to the increase in clandestine amphetamine manufacture, there were increased seizures of ephedrine tablets which are used to synthesis amphetamine, made by the New Zealand Customs Service from 10,308 tablets in 2000, to 32,653 tablets in 2001, to 830,320 tablets in 2003.3,4 Trends in drug seizures, however, can be influenced by the resources and attention dedicated to a drug type by law enforcement agencies, and consequently they are not necessarily an accurate measure of population trends in the use of a drug.
International studies have shown that chronic or high-dose use of amphetamines can cause hostility, violence, audio and visual hallucinations, and a paranoid psychosis resembling schizophrenia. In addition they can cause damage to cardiac, vascular, and neurological systems.5–10
In New Zealand, the growing use of amphetamine has been linked to a range of public health and social problems including mental illness, drug dependence, intravenous drug use, family break-down, violence, and property crime.2,11,12,13
The continued rise in detections of local amphetamine laboratories and related precursor chemicals since 2001 has led to considerable public anxiety about the eventual level of amphetamine use in New Zealand. For example, some sources quoted by the popular media have suggested that amphetamine use may continue to increase to a point where it replaced cannabis as New Zealand’s most widely used illicit drug.19
In 2002, the government and law enforcement agencies initiated several legislative and strategic responses to the rise in amphetamine use, with a particular focus on domestic methamphetamine manufacture and use.3
The aim of this paper is to track recent trends in the population prevalence, availability, price, and harm of amphetamine in New Zealand. The analysis is carried out using data from the three most recent waves of New Zealand national household drug surveying conducted in 1998, 2001, and 2003 respectively.

Method

National household drug surveying was conducted in New Zealand in 1998, 2001, and 2003. The 1998 and 2001 surveys were funded from contestable research funds and were known as the National Drug Survey (NDS). The 2003 wave of surveying was directly funded by the Ministry of Health and was renamed the Health Behaviours Survey-Drug Use (2003 HBS-Drug Use). The 2003 HBS-Drug Use retained the same Computer Assisted Telephone Interview (CATI) survey methodology and core sections of the questionnaire from the NDS. The age range of the 2003 HBS-Drug Use sample was extended from the age ranges surveyed by the NDS (i.e. 15–45 years in 1998 and 13–45 years in 2001) to include 13–65 year olds.
To allow valid comparisons back to the 1998 NDS, the age range of the 2003 HBS-Drug Use sample and 2001 NDS sample were truncated to those aged 15–45 years old. The 1998 NDS and 2003 HBS-Drug Use included extended samples of Maori to allow detailed comparisons of Maori and non-Maori.
To ensure valid comparisons between all three survey waves, only the general population random digit dial (RDD) samples from each survey wave were compared. Interviewing for the RDD sampling was conducted between April and September in each survey wave to replicate any seasonal variation in drug use.
All three waves of RDD sampling employed the same CATI sampling methodology. Telephone numbers were selected using a stratified random digit dialling method so that each household, of a particular stratum, nationwide had an equal chance of being called. The country was divided into a number of strata based on telephone exchanges to represent the different socioeconomic characteristics of the population. A proportionate sample from each stratum was then taken.
Within each household, one person was randomly selected for an interview. Each telephone number was tried at least 10 times on different dates and times of the day in an effort to reach those seldom at home. Respondents were informed that the study was being conducted on behalf of the Ministry of Health and that everything they said would be confidential.
In each survey wave, participants were asked the same questions concerning whether they had ever used amphetamine and whether they had used amphetamine in the last 12 months. The questions about amphetamine referred to the broad class of the amphetamines which the interviewer described to the respondent as ‘amphetamines, uppers, speed, methamphetamine’.
Additional questions on amphetamine were included in the 2001 and 2003 waves of surveying, including questions on whether the availability and price of amphetamine had changed compared to 12 months ago, and whether the use of amphetamine had harmed eight areas of a user’s life in the previous 12 months. The respective sample sizes for each survey wave were: 5475 in 1998; 5504 in 2001 and 3042 in 2003. The response rates for the survey waves were 79% in 1998, 80% in 2001, and 68% in 2003. (This is the response rate for the general sample of 2003 HBS-Drugs which was collected in the age range 13–65 years old. It was not possible to recalculate the response rate for the truncated age range as we could not distinguish the non-response by age.)

Analysis

All three samples were weighted by the number of people within the household who were eligible for each survey to adjust for the selection of only one person per household. Prevalence levels and confidence intervals were calculated using logistic regression, accounting for the effects of weighting and stratification.
Two sample t-tests were used, based on the logistic regression summary statistics, to test for differences between the samples. There were three t-tests per prevalence level; one for each two-way combination of the three samples. When comparing more than two groups, the probability of making a type 1 error increases if not adjusted for. Consequently when comparisons were made between the 3 years, values are only reported as significant when the p value <0.017. This value was calculating using the Sidak-Bonferroni method.
where is the desired overall alpha level and n is the number of groups
In this case
Where comparisons are only made between two survey years, differences have been reported if the p value <0.05. The error bars on the graphs indicate the 95% confidence intervals. All analysis was run in the SAS and SUDAAN statistical software packages.

Results

Prevalence of amphetamine use—The proportion of the sample who had ever used amphetamine increased in 2001 compared to 1998 (11.0% versus 7.6%, p<0.0001) and then decreased in 2003 compared to 2001 (9.0% versus 11.0%, p=0.0066). By age group, there was an increase in those who had ever tried amphetamine in 2001 compared to 1998 among those aged 20–24 years old (from 16.2% versus 8.5%, p<0.0001).
The last-year use of amphetamine increased in 2001 compared to 1998 (5.0% versus 2.9%, p<0.0001) and then did not change in 2003 compared to 2001 (4.0% versus 5.0%, p=0.0466). The last-year use of amphetamine increased between 1998 and 2001 for those aged 15–19 years old (4.0% versus 7.5%, p=0.0078), 20–24 years old (5.8% versus 10.5%, p=0.004), and 35-45 years old (0.6% versus 1.5%, p=0.0084) (Figure 1).
Change in the availability of amphetamine—The proportion of those who had used amphetamine in the last year who said that the availability of amphetamine had become ‘harder’ compared to 12 months ago was higher in 2003 compared to 2001 (24.5% versus 12.4%, p=0.0284) (Figure 2). In 2003, as in 2001, nearly half of the last-year amphetamine users reported the availability of amphetamine was ‘easier’ compared to a year ago. In 2003, 3 out of 10 (29.0%) last-year amphetamine users reported the availability of amphetamine was the ‘same’ as a year ago.
Figure 1. Last year use of amphetamine by age, 1998, 2001, and 2003
Figure 2. Change in the availability of amphetamine compared to a year ago, 2001, and 2003
Change in price of amphetamine—There was no change in the perceptions of the price of amphetamine by last-year amphetamine users in 2003 compared to 2001. In 2003, 6 out of 10 last-year amphetamine users (61.7%) described the price of amphetamine as the ‘same’ compared to a year ago; 1 in 4 (24.8%) last-year amphetamine users said the price was ‘lower’ and 1 in 8 (13.4%) said the price was ‘higher’ compared to a year ago.
Harms from amphetamine use—There was no difference in the proportion of last-year amphetamine users reporting harm in different areas of their life from amphetamine use in 2003 compared to 2001 (Table 1).
Table 1. Last-year amphetamine users who reported areas of their life harmed from amphetamine use in the last 12 months
Area of life
2001
2003
Energy and vitality
Financial position
Health
Friendships and social life
Outlook on life
Home life
Work or work opportunities
Children’s health or wellbeing
At least one area
19.4
12.3
9.7
7.1
5.9
3.6
3.7
0.6
29.3
16.7
14.4
9.9
7.4
8.0
5.8
5.4
2.4
29.5
In 2003, as in 2001, harm to ‘energy and vitality’, ‘financial position’, and ‘health’ were the areas of life most commonly reported harmed from amphetamine use. Three out of 10 of those who had used amphetamine in the last year had experienced harm to at least one of the areas of life asked about in both 2001 and 2003.

Discussion

The comparisons of the three waves of New Zealand national household drug surveying indicate a general rise in the initiation of (and last-year use of) amphetamine use in New Zealand in 2001 compared to 1998. This was followed by a levelling out in levels of last-year use of amphetamine in 2003 compared to 2001.
In 2003, more last-year amphetamine users reported that the availability of amphetamine had become more difficult compared to the preceding 12 months, than in 2001. However, in 2003, as in 2001, nearly half of the users reported that the availability of amphetamine had become ‘easier’ compared to a year ago.
Approximately 6 out of 10 last-year users in 2001 and 2003 reported the price of amphetamine was the ‘same’ compared to 12 months ago. Similar proportions of last-year amphetamine users reported harm in different areas of their life in 2001 and 2003 from their amphetamine use. In both survey waves, approximately 1 in 5 last-year users reported harm to ‘energy and vitality’(and 1 in 10 reported harm to ‘health’) due to their amphetamine use in the last 12 months.
The validity of the comparisons between the waves of national household drug surveying relies on the exact replication of the survey methodology for each wave. This ensures that any differences found between the waves represent real changes in drug use and are not due to any change in the way the survey was conducted.
As detailed in the methodology section, all three RDD general population samples employed the same CATI survey methodology, asked the same questions about amphetamine use, and were collected during the same months of the year. The extended age ranges of the 2003 HBS-Drug Use and 2001 NDS were truncated to match the 15–45 year olds surveyed in the 1998 NDS.
While replication of the CATI survey methodology allows valid comparisons between the survey waves, we acknowledge that household drug surveys in general are likely to underestimate the true extent of drug use to some extent. This is largely due to the difficulties of reaching heavier drug users who are more likely to be homeless, incarcerated, or be difficult to contact in general.31
There were some differences between the survey waves in regard to the performance of the survey methodology. The response rate of the survey fell in 2003 compared to previous years. One factor in the decline in the response rate of the survey may have been the increase in private telephone market surveying in New Zealand over this time, which inadvertently competes with social science surveying for respondents’ time and patience. It might be speculated that drug users may be less likely to want to participate in the survey and consequently are more likely to be non-responders.
Increasing stigmatisation of methamphetamine as result of a number of high-profile violent crimes attributed to methamphetamine use and psychosis, and the reclassification of methamphetamine to Class A, may have also contributed to declining response rates and willingness to admit amphetamine use. The higher non-response in 2003 may have caused some underestimation of drug use in 2003 compared to other years. However, given the magnitude of the difference in non-response between 2003 and 2001 (i.e. 12%), even assuming a much higher prevalence of amphetamine use among the non-responders compared to the survey sample, it would be unlikely to change the outcome of the statistical tests. The last-year use of amphetamine among the non-responders in 2003 would have to be over 15% (compared to 4% within the responders) to result in a statistically significant increase in amphetamine use in 2003 compared to 2001.
In each wave of the survey, the age, gender, and ethnicity of the survey sample was compared with respective Census population figures or (where appropriate) Census population estimates.14,15 In the 1998 and 2001 waves, the weighted survey sample had a slightly higher proportion of males than the Census population figures. About two-thirds of amphetamine users in each survey wave were male,12,16,17 so the lower proportion of males in the weighted sample in 2003 compared to previous waves may have caused a very small underestimation of amphetamine use. Again these differences were not considered large enough to make a difference to the results of the statistical tests completed.
Two types of environmental change may have played a part in the stabilisation of use (and the relative decline in levels of availability) of amphetamine in New Zealand in 2003 compared to 2001. The first is a growing awareness among the youth and drug-using population concerning the health risks and disutility of methamphetamine use over the medium and long term. Chronic heavy methamphetamine users are at high risk of experiencing serious psychological problems from their drug use, such as acute psychosis, extreme paranoia, aggression, and dependence.8,20
A recent convenience sample of frequent methamphetamine users (n=78) interviewed from five centres in New Zealand found that 58% reported ‘short temper’, 56% ‘paranoia’, 51% ‘anxiety’, 43% ‘depression’, and 22% ‘suicidal thoughts’ related to their methamphetamine use in the last 6 months.32
In 2002, methamphetamine use was implicated in a series of rather bizarre and extremely violent crimes in New Zealand committed by individuals under the influence of methamphetamine or suffering methamphetamine-induced psychosis. These crimes included a multiple homicide, unprovoked stranger murder, and samurai sword attack and murder. These criminal incidents and their link with the newly emerging methamphetamine received extensive coverage in the local media.19
Studies of amphetamine users in other countries have found that the negative mental health effects of amphetamine-use (such as aggression, paranoia, and depression), rather than physical harms from use, were the problems that caused the greatest concern among users and were most likely to cause them to seek help for their drug use.20 This sensitivity was thought to be related to the value young people placed on acceptance by their peer group and the effect that behavioural abnormalities could have on these relationships.20
The highly publicised mental health effects of methamphetamine use may have damaged the reputation of methamphetamine as a manageable risk among some drug users and young people in New Zealand after 2001. A drug’s reputation or image is considered to be central to fuelling a drug epidemic by encouraging the curious to start use, and reinforcing current users desire to continue and escalate their use.21–23
Accounts of amphetamine trends in Japan, Australia, and the United States have identified the relative rapidity with which new amphetamine users discover the negative mental health effects of amphetamine use, and the often shocking criminal incidents associated with amphetamine-induced psychosis, as factors which have tended to contribute to the relative short time span of amphetamine epidemics.21,24–26
Secondly, following the rise in amphetamine use in 2001 there was a concerted law enforcement and legislative response to this drug type in New Zealand, with a particular focus on the locally manufactured methamphetamine.3
New Zealand Police negotiated a series of protocols with the Pharmaceutical Guild to control and monitor the over-the-counter sale of ephedrine-based flu medicines from pharmacies, as these products were been used as sources of ephedrine to synthesis methamphetamine.4
Three specialised police teams were established in 2002 to detect and dismantle clandestine methamphetamine laboratories.3 With the emergence of large-scale domestic methamphetamine manufacture, New Zealand Customs paid greater attention to the importation of ephedrine, products containing ephedrine, and other chemical precursors used in methamphetamine manufacture.
In early 2003, the New Zealand Parliament reclassified methamphetamine (from a Class B to a Class A drug offence) under the Misuse of Drugs Act 1975. A Class A drug offence is the highest offence class; it carries a maximum penalty of life imprisonment for trafficking and manufacture.
Changes to the Misuse of Drugs Act 1975 were also enacted to increase the powers of the police and customs to search and seize unlicensed imports of ephedrine and other chemicals used to synthesis methamphetamine. A strong law enforcement and legislative response to a sudden rise in amphetamine use has been discussed as a factor which has assisted in the control of outbreaks of amphetamine use in other countries at other times.23,24,26–30
Amphetamine remains a drug of serious concern in New Zealand. As noted here, chronic heavy methamphetamine use is associated with aggression and serious psychological problems with implications for violence, crime, and neglect of responsibility.
One in 10 New Zealanders aged 20–24 years old had used amphetamine in the last year in 2003, and approximately 3 out 10 last-year users experience harm in at least one area of their life in the preceding 12 months. There is evidence of a levelling out in the prevalence of amphetamine use and some evidence of a relative decline in the availability of amphetamine in New Zealand. This may reflect greater awareness of the health risks of methamphetamine use and a greater law enforcement focus on methamphetamine in recent years. The levelling out of amphetamine use in 2003 may well be only a temporary phenomenon, however.
The impact of the shocking criminal incidents and stiffer regulatory controls related to amphetamine may fade over the coming years. A number of countries which have historically had problems with amphetamine use have experienced recurring amphetamine epidemics as new generations of young people rediscover the attractive features of amphetamine while having little sub-cultural memory of the hazards of use.23–25,28,30
Acknowledgements: We acknowledge several funding sources and individuals who made this analysis possible. The 2003 National Household Drug Survey was reconfigured as the 2003 Health Behaviours Survey–Drug Use Survey and was funded by the Ministry of Health and carried out as part of the Public Health Intelligence (PHI) Health Behaviours Survey Monitor. The statistical design and analysis for the 2003 survey was completed by Megan Pledger and Paul Sweetsur at the Centre for Social and Health Outcomes Research and Evaluation (SHORE), Massey University, and by James Reilly at Statistical-Insights.
Data collection was managed by Chris Wilkins, Rachael Lane, Joe Morley, and Mary Blade. The 2001 New Zealand National Drug Survey was a project of the Alcohol & Public Health Research Unit (APHRU) at the University of Auckland, and was funded by the Health Research Council (HRC) and the Alcohol Advisory Council of New Zealand.
The funding to conduct the survey was awarded to Sally Casswell as an investigator-initiated research grant. The 2001 survey was led by Chris Wilkins with Rachael Lane, Mary Blade, and Heather Seal. The data management and weighting for the 2001 survey were carried out by Krishna Bhatta and Megan Pledger (assisted by Michael Ford and Alistair Stewart).
The 1998 New Zealand National Drug Survey was a project of the APHRU at the University of Auckland, and was funded as a core programme of the HRC and the Alcohol Advisory Council. The funding to conduct the survey was provided in part by the HRC as an investigator-initiated research grant to Sally Casswell, and in part by the Ministry of Health.
The 1998 survey was led by Adrian Field with Brendon Dacey and Francesa Holibar. The data management and weighting for the 1998 survey were carried out by Jia-fang Zhang, Michael Ford, and Krishna Bhatta (assisted by Allan Wyllie).
Subsequent secondary analysis of the three national household drug surveys was funded by New Zealand Police in 2005. Last but not least, we acknowledge the time and willingness of the New Zealand public to respond to all the survey waves, without which none of the surveys would have taken place.
Author information: Chris Wilkins, Senior Researcher; Paul Sweetsur, Statistician; Sally Casswell, Director; Centre for Social and Health Outcomes Research and Evaluation (SHORE), Massey University, Auckland
Correspondence: Dr Chris Wilkins, Centre for Social and Health Outcomes Research and Evaluation (SHORE), Massey University, PO Box 6137, Wellesley Street, Auckland. Fax: (09) 366 5149; email: c.wilkins@massey.ac.nz.
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