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On the other handThe hand you favour as a 10-week-old
fetus is the hand you will favour for the rest of your life. The finding comes
as a surprise because it had been thought that lifelong hand preferences did not
develop until a child was 3 or 4 years old. A team led by Peter Hepper of the
Fetal Behavioural Research Centre at Queen’s University, Belfast in the UK
reached this conclusion after studying ultrasound scans of 1000 fetuses. In one
study, nine out of 10 fetuses at 15 weeks’ gestation preferred to suck
their right thumbs. Hepper’s team followed 75 of those fetuses after
birth, and found that at 10 to 12 years old all 60 of the right thumb-suckers
were right handed, while 10 of the 15 left thumb-suckers were left handed and
the rest right handed.
New
Scientist, 24 July 2004
Tonsillectomy and postoperative haemorrhageApparently diathermy and coblation
(a variation of electrosurgery with lower tissue temperatures than diathermy)
have overtaken dissection as the favoured tonsillectomy techniques. However, in
a recent overview of 252 hospitals in England and N. Ireland it has been found
that the overall haemorrhage rate was 3.1 times higher with diathermy
tonsillectomy than with cold steel tonsillectomy without any use of diathermy
(p<0.001). The corresponding relative risk for coblation tonsillectomy was
3.4; p<0.001). When cold steel was used for dissection and diathermy only for
haemostasis the relative risk was 2.2. (p=0.002). Therefore the authors
recommend that these newer methods should be used with appropriate caution and
only after proper training.
Lancet
2004;364:697–702
Graduate vs conventional entry to medical school?In a study from the University of
Newcastle (New South Wales, Australia) the careers of the first 16 years’
graduates have been evaluated. The researchers found no significant differences
between graduate and conventional entrants in terms of academic performance (as
measured by the award of medical school honours) or research outcomes (as
measured by completion of a research degree during or after medical school
training, publication of scientific papers or holding career posts in the
research sciences).
There were no differences in career positions held by
clinicians, choice of general practice or another specialty as a career,
practice location (rural or urban) or employment sector (public or private).
They found no clear advantage, at least on the outcomes measured in this study,
to limiting medical school entry to either group and felt that medical schools
could reasonably broaden their selection criteria to include more graduate entry
candidates.
Medical
Education 2004:38:778–86.
Evidence based bad medicineThe Randomized Aldactone Evaluation
Study (RALES) demonstrated that spironolactone significantly improves outcomes
in patients with severe heart failure. Use of angiotensin-converting-enzyme
(ACE) inhibitors is also indicated in these patients.
That is the good news. The down side is that these patients
are susceptible to the development of hyperkalaemia. In a paper from Canada it
has been demonstrated that after the publication of RALES there was an increase
in the rate of hospitalisation for hyperkalaemia from 2.4/1000 patients to
11/1000 patients (p<0.001) and a commensurate increase in deaths in these
patients. Unlike the selected trial patients, older patients with renal
impairment and those on potassium supplements should not have spironolactone and
all should have regular biochemical blood tests.
N
Engl J Med 2004;351:543-51
Polio about face in NigeriaThe Nigerian government came under
severe pressure last year from radical Muslim leaders opposed to the
immunisation campaign on the grounds that the vaccines contained antifertility
substances, which they contended may have been targeted mainly at the Muslim
population in northern Nigeria.
The bickering led to a suspension in August 2003 of a UN
backed campaign to eradicate polio by the end of 2004. This resulted in a marked
increase in the number of polio infected and paralysed children and the
reinfection of previously polio free states in Nigeria and exportation of the
virus in at least six neighbouring countries.
However, in July the Nigerian Health Minister apologised on
behalf of the Nigerian government for this development and at the same time
pledge to work harder to make polio history by the end of this year.
BMJ
2004:329:365
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